Jacob: Jacob knew that he was not himself. For weeks he had felt edgy. His mood was all over the place. One minute he was happy. A short while later he would have tears in his eyes. He wasn't depressed. But everything affected him much more than was usual for him. He was too sensitive to anything that occurred.

His wife and children knew that something was wrong. They found him short tempered and irritable. For the past two weeks, he was awake late into the night. "It is like I can not turn my mind off," Jacob complained. "I guess that I was not as prepared for the kidney transplant as I had thought. I don't seem to be coping very well."

This describes some mental side effects that occur commonly with Prednisone. Jacob was taking Prednisone each day to avoid organ rejection. Unfortunately, he was not aware that these changes could result from Prednisone. Like many others, he assumed that his difficulty resulted from some failure on his own part to deal with transplantation.

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